A 380 m³ pharmaceutical production suite consisting of various production and processing equipment was decontaminated with chlorine dioxide gas after a contamination was discovered. Even after thorough cleaning and liquid decontamination, a persistent salmonella problem could not be eradicated. Decon-O-logic was able to fumigate the facility utilizing chlorine dioxide gas and eliminate the organisms while providing sporicidal kill of Biological Indicators (comprised of bacillus atrophaeus spores) placed throughout the facility to ensure the process was successful.